Disproportionate Decline of Executive Functions in Early Mild Cognitive Impairment, Late Mild Cognitive Impairment, and Mild Alzheimer’s Disease
نویسندگان
چکیده
منابع مشابه
Executive functions deficit in mild cognitive impairment.
OBJECTIVE To investigate whether patients diagnosed with amnestic mild cognitive impairment (MCI) have also impairment in attention/executive functions, and therefore to clarify whether all subcomponents of executive control are equally affected in MCI. BACKGROUND MCI refers to the transitional state between normal aging and dementia. Amnestic MCI is characterized by impaired episodic memory,...
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OBJECTIVE To characterize the course of cognitive decline during the prodromal phase of Alzheimer disease. DESIGN Longitudinal cohort study with up to 16 years of observation. PARTICIPANTS Older persons from 2 studies underwent annual clinical evaluations that included cognitive function testing and clinical classification of mild cognitive impairment, dementia, and Alzheimer disease. At ba...
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Background/Aims: Proverb interpretation is assumed to reflect executive functions. We hypothesized that proverb interpretation is impaired in patients with amnestic mild cognitive impairment (aMCI) diagnosed as single-domain impairment by common neuropsychological testing. Methods: We compared performance in a proverb interpretation test in single-domain aMCI patients and patients with early Al...
متن کاملImpairment in Proverb Interpretation as an Executive Function Deficit in Patients with Amnestic Mild Cognitive Impairment and Early Alzheimers Disease
Background/Aims: Proverb interpretation is assumed to reflect executive functions. We hypothesized that proverb interpretation is impaired in patients with amnestic mild cognitive impairment (aMCI) diagnosed as single-domain impairment by common neuropsychological testing. Methods: We compared performance in a proverb interpretation test in single-domain aMCI patients and patients with early Al...
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OBJECTIVE To examine the relationship between body mass index (BMI) and cognitive decline in subjects diagnosed with mild cognitive impairment (MCI). METHODS Neuropsychologic and clinical evaluations were conducted at baseline, 6-months, and 1-year on 286 MCI subjects enrolled in the Alzheimer's Disease Neuroimaging Initiative. A global cognitive composite score was derived (mean Z-score) fro...
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ژورنال
عنوان ژورنال: Dementia and Neurocognitive Disorders
سال: 2016
ISSN: 1738-1495,2384-0757
DOI: 10.12779/dnd.2016.15.4.159